CLEARTEST Calprotectin

With an inflammation within the bowel, immune cells are being lured into the intestinal wall with the help of tissue hormones, to fight against any possible virus. With the aid of these immune cells doctors can determine the quantity of the biomarker calprotectin.

The CLEARTEST Calprotectin is a rapid test for the detection of a bowel disease from the stool sample.

Calprotectin, also named human leucocytes protein, is in the inner of the neutrophil granulocytes and has amongst other things an antimicrobial effect.

With help of the biomarker calprotectin, from which it is possible to infer indirectly to the faecal immune cells, the doctor receives information about the intestinal inflammatory activity.

An increased calprotectin value (> 50 µg per gram stool) indicates an inflammatory bowel disease, as there are Crohn's disease, ulcerative colitis, diverticulitis, etc., as well as their inflammatory processes.

Storage at 2 °C - 30 °C

Evaluation after5 minutes

Cut off: 50 µg/g stool

The reasons for a raised calprotectin value for instances may be:

Colitis ulcerosa or Morbus Crohn

A viral or bacterial infection of the gastro-intestinal system

Diverticulitis

Cancer diseases

As well diseases of the digestive system may cause raised calprotectin values.

Storage at 2°C - 30 °C

Evaluation after 5 minutes

Cut off: 50 µg/g stool